Malignancy risk models for oral lesions
نویسندگان
چکیده
منابع مشابه
Malignancy Risk Models for Oral Lesions
OBJECTIVES The aim of this work was to assess risk habits, clinical and cellular phenotypes and TP53 DNA changes in oral mucosa samples from patients with Oral Potentially Malignant Disorders (OPMD), in order to create models that enable genotypic and phenotypic patterns to be obtained that determine the risk of lesions becoming malignant. STUDY DESIGN Clinical phenotypes, family history of c...
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Oral leukoplakia, oral submucous fibrosis and erythroplakia are 3 major types of oral premalignant lesions. Multiple oral premalignant lesions may possibly develop due to field cancerization, where carcinogenic exposures can cause simultaneous genetic defects to the upper aerodigestive tract epithelium, putting the epithelium at high risk for development of premalignant lesions at different sta...
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CONTEXT The size of colorectal lesions, besides a risk factor for malignancy, is a predictor for deeper invasion objectives: To evaluate the malignancy of colorectal lesions ≥20 mm. METHODS Between 2007 and 2011, 76 neoplasms ≥20 mm in 70 patients were analyzed. RESULTS The mean age of the patients was 67.4 years, and 41 were women. Mean lesion size was 24.7 mm ± 6.2 mm (range: 20 to 50 mm)...
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BACKGROUND AND AIM: Epidemiological studies have established a wide variation in the prevalence of oral lesions in different population. Officially oral mucosa diseases can occur in 25-50% of cases, depending on the population to which the survey was conducted. We examined the relationship between oral mucosal lesions, tongue pH level, gingivitis, oral hygiene, and oral health behaviors in stud...
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BACKGROUND In light of the recently found contribution of angiogenic and inflammation-related factors to malignancies, this study investigated the possible association of the angiotensinogen gene (AGT) with increased risk of oral cancer. MATERIALS AND METHODS The M235T polymorphism, which influences AGT gene expression, was evaluated by restriction fragment length polymorphism analysis in the...
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ژورنال
عنوان ژورنال: Medicina Oral Patología Oral y Cirugia Bucal
سال: 2013
ISSN: 1698-6946
DOI: 10.4317/medoral.18374